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Phase 1 studies to assess the safety, tolerability and pharmacokinetics of JTE‐052 (a novel Janus kinase inhibitor) ointment in Japanese healthy volunteers and patients with atopic dermatitis

The purpose of the present two phase 1 studies was to assess the safety, tolerability and pharmacokinetics for topical application of a novel Janus kinase (JAK) inhibitor, JTE‐052, in Japanese healthy adult male volunteers and Japanese adult patients with atopic dermatitis (AD). Additionally, explor...

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Detalles Bibliográficos
Autores principales: Nakagawa, Hidemi, Nemoto, Osamu, Yamada, Hiroyuki, Nagata, Takeshi, Ninomiya, Noriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001687/
https://www.ncbi.nlm.nih.gov/pubmed/29665062
http://dx.doi.org/10.1111/1346-8138.14322