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Upregulation of P2Y(2)R, Active uPA, and PAI-1 Are Essential Components of Hantavirus Cardiopulmonary Syndrome

Sin Nombre virus (SNV) causes hantavirus cardiopulmonary pulmonary syndrome (HCPS) with the loss of pulmonary vascular endothelial integrity, and pulmonary edema without causing cytopathic effects on the vascular endothelium. HCPS is associated primarily with a dysregulated immune response. We previ...

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Detalles Bibliográficos
Autores principales: Bondu, Virginie, Bitting, Casey, Poland, Valerie L., Hanson, Joshua A., Harkins, Michelle S., Lathrop, Sarah, Nolte, Kurt B., Lawrence, Daniel A., Buranda, Tione
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001748/
https://www.ncbi.nlm.nih.gov/pubmed/29930915
http://dx.doi.org/10.3389/fcimb.2018.00169