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Structures and disulfide cross‐linking of de novo designed therapeutic mini‐proteins
Recent advances in computational protein design now enable the massively parallel de novo design and experimental characterization of small hyperstable binding proteins with potential therapeutic activity. By providing experimental feedback on tens of thousands of designed proteins, the design‐build...
Autores principales: | Silva, Daniel‐Adriano, Stewart, Lance, Lam, Kwok‐Ho, Jin, Rongsheng, Baker, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001749/ https://www.ncbi.nlm.nih.gov/pubmed/29389072 http://dx.doi.org/10.1111/febs.14394 |
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