Identifying Small‐Molecule Binding Sites for Epigenetic Proteins at Domain–Domain Interfaces

Epigenetics is a rapidly growing field in drug discovery. Of particular interest is the role of post‐translational modifications to histones and the proteins that read, write, and erase such modifications. The development of inhibitors for reader domains has focused on single domains. One of the maj...

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Detalles Bibliográficos
Autores principales: Bowkett, David, Talon, Romain, Tallant, Cynthia, Schofield, Chris, von Delft, Frank, Knapp, Stefan, Bruton, Gordon, Brennan, Paul E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001751/
https://www.ncbi.nlm.nih.gov/pubmed/29578648
http://dx.doi.org/10.1002/cmdc.201800030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001751/
https://www.ncbi.nlm.nih.gov/pubmed/29578648
http://dx.doi.org/10.1002/cmdc.201800030

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