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Molecular Basis for Dysregulated Activation of NKX2‐5 in the Vascular Remodeling of Systemic Sclerosis

OBJECTIVE: NKX2‐5 is a homeobox transcription factor that is required for the formation of the heart and vessels during development, with significant postnatal down‐regulation and reactivation in disease states, characterized by vascular remodeling. The purpose of this study was to investigate mecha...

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Detalles Bibliográficos
Autores principales: Dritsoula, Athina, Papaioannou, Ioannis, Guerra, Sandra G., Fonseca, Carmen, Martin, Javier, Herrick, Ariane L., Abraham, David J., Denton, Christopher P., Ponticos, Markella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001790/
https://www.ncbi.nlm.nih.gov/pubmed/29342503
http://dx.doi.org/10.1002/art.40419