Cargando…

Atrial natriuretic peptide modified oleate adenosine prodrug lipid nanocarriers for the treatment of myocardial infarction: in vitro and in vivo evaluation

PURPOSE: Myocardial infarction is a major cause of mortality and heart failure worldwide. One of the most effective methods of this injury is direct delivery of cardioprotective drugs to ischemia–reperfusion (IR) myocardium. The aim of the present study was to fabricate an adenosine (Ade) prodrug-ba...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Jianjun, Li, Wei, Yu, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001834/
https://www.ncbi.nlm.nih.gov/pubmed/29928113
http://dx.doi.org/10.2147/DDDT.S166749