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Sirtuin-4 (SIRT4), a therapeutic target with oncogenic and tumor-suppressive activity in cancer

Several members of the sirtuin (SIRT) family, a highly conserved family of NAD(+)-dependent enzymes, have been shown to play a critical role in both promoting and/or suppressing tumorigenesis. In this study, recent progress in the field concerning SIRT4 and cancer was reviewed, and the relationship...

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Detalles Bibliográficos
Autores principales: Huang, Guoyu, Zhu, Guanbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001835/
https://www.ncbi.nlm.nih.gov/pubmed/29928130
http://dx.doi.org/10.2147/OTT.S157724