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Pharmacokinetics and pharmacodynamics of linezolid in plasma/cerebrospinal fluid in patients with cerebral hemorrhage after lateral ventricular drainage by Monte Carlo simulation

OBJECTIVE: We investigated the pharmacokinetic (PK) and pharmacodynamic (PD) parameters of linezolid in patients who had suffered cerebral hemorrhage after lateral ventricular drainage. MATERIALS AND METHODS: Ten patients with cerebral hemorrhage after lateral ventricular drainage with stroke-associ...

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Detalles Bibliográficos
Autores principales: Wu, Xiaofei, Tang, Yan, Zhang, Xiaohua, Wu, Chenchen, Kong, Lingti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001839/
https://www.ncbi.nlm.nih.gov/pubmed/29928111
http://dx.doi.org/10.2147/DDDT.S168757