Effect of food on the pharmacokinetic characteristics of a single oral dose of LCB01-0371, a novel oxazolidinone antibiotic

BACKGROUND: LCB01-0371 is a novel oxazolidinone antibiotic that blocks protein production by binding to bacterial 23S ribosomes. This antibiotic is active against Gram-positive bacteria. This study aimed to evaluate the effect of food on the pharmacokinetics (PKs) of LCB01-0371 and evaluate its safe...

Descripción completa

Detalles Bibliográficos
Autores principales: Sunwoo, Jung, Kim, Yu Kyong, Choi, Yewon, Yu, Kyung-Sang, Nam, Heesook, Cho, Young Lag, Yoon, Seonghae, Chung, Jae-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001845/
https://www.ncbi.nlm.nih.gov/pubmed/29928114
http://dx.doi.org/10.2147/DDDT.S155657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001845/
https://www.ncbi.nlm.nih.gov/pubmed/29928114
http://dx.doi.org/10.2147/DDDT.S155657

Ejemplares similares