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Effect of food on the pharmacokinetic characteristics of a single oral dose of LCB01-0371, a novel oxazolidinone antibiotic
BACKGROUND: LCB01-0371 is a novel oxazolidinone antibiotic that blocks protein production by binding to bacterial 23S ribosomes. This antibiotic is active against Gram-positive bacteria. This study aimed to evaluate the effect of food on the pharmacokinetics (PKs) of LCB01-0371 and evaluate its safe...
Autores principales: | Sunwoo, Jung, Kim, Yu Kyong, Choi, Yewon, Yu, Kyung-Sang, Nam, Heesook, Cho, Young Lag, Yoon, Seonghae, Chung, Jae-Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001845/ https://www.ncbi.nlm.nih.gov/pubmed/29928114 http://dx.doi.org/10.2147/DDDT.S155657 |
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