Loss of dorsomedial hypothalamic GLP-1 signaling reduces BAT thermogenesis and increases adiposity

OBJECTIVE: Glucagon-like peptide-1 (GLP-1) neurons in the hindbrain densely innervate the dorsomedial hypothalamus (DMH), a nucleus strongly implicated in body weight regulation and the sympathetic control of brown adipose tissue (BAT) thermogenesis. Therefore, DMH GLP-1 receptors (GLP-1R) are well...

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Detalles Bibliográficos
Autores principales: Lee, Shin J., Sanchez-Watts, Graciela, Krieger, Jean-Philippe, Pignalosa, Angelica, Norell, Puck N., Cortella, Alyssa, Pettersen, Klaus G., Vrdoljak, Dubravka, Hayes, Matthew R., Kanoski, Scott E., Langhans, Wolfgang, Watts, Alan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001878/
https://www.ncbi.nlm.nih.gov/pubmed/29650350
http://dx.doi.org/10.1016/j.molmet.2018.03.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001878/
https://www.ncbi.nlm.nih.gov/pubmed/29650350
http://dx.doi.org/10.1016/j.molmet.2018.03.008

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