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Female sex hormones are necessary for the metabolic effects mediated by loss of Interleukin 18 signaling

OBJECTIVE: Interleukin (IL)-18 plays a crucial role in maintaining metabolic homeostasis and levels of this cytokine are influenced by gender, age, and sex hormones. The role of gender on IL-18 signaling, however, is unclear. We hypothesized that the presence of female sex hormone could preserve the...

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Detalles Bibliográficos
Autores principales: Lindegaard, Birgitte, Abildgaard, Julie, Heywood, Sarah E., Pedersen, Bente K., Febbraio, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001917/
https://www.ncbi.nlm.nih.gov/pubmed/29699928
http://dx.doi.org/10.1016/j.molmet.2018.04.005