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Characterization of a non-nudix pyrophosphatase points to interplay between flavin and NAD(H) homeostasis in Saccharomyces cerevisiae

The flavin cofactors FMN and FAD are required for a wide variety of biological processes, however, little is known about their metabolism. Here, we report the cloning and biochemical characterization of the Saccharomyces cerevisiae pyrophosphatase Fpy1p. Genetic and functional studies suggest that F...

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Detalles Bibliográficos
Autores principales: Lynch, Joseph H., Sa, Na, Saeheng, Sompop, Raffaelli, Nadia, Roje, Sanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002036/
https://www.ncbi.nlm.nih.gov/pubmed/29902190
http://dx.doi.org/10.1371/journal.pone.0198787