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Modeling human early otic sensory cell development with induced pluripotent stem cells

The inner ear represents a promising system to develop cell-based therapies from human induced pluripotent stem cells (hiPSCs). In the developing ear, Notch signaling plays multiple roles in otic region specification and for cell fate determination. Optimizing hiPSC induction for the generation of a...

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Detalles Bibliográficos
Autores principales: Lahlou, Hanae, Lopez-Juarez, Alejandra, Fontbonne, Arnaud, Nivet, Emmanuel, Zine, Azel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002076/
https://www.ncbi.nlm.nih.gov/pubmed/29902227
http://dx.doi.org/10.1371/journal.pone.0198954