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Assessment of ab initio models of protein complexes by molecular dynamics

Determining how proteins interact to form stable complexes is of crucial importance, for example in the development of novel therapeutics. Computational methods to determine the thermodynamically stable conformation of complexes from the structure of the binding partners, such as RosettaDock, might...

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Detalles Bibliográficos
Autores principales: Radom, Filip, Plückthun, Andreas, Paci, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002105/
https://www.ncbi.nlm.nih.gov/pubmed/29864135
http://dx.doi.org/10.1371/journal.pcbi.1006182