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Integrin αvβ6 Promotes Lung Cancer Proliferation and Metastasis through Upregulation of IL-8–Mediated MAPK/ERK Signaling()

Lung cancer is notorious for high morbidity and mortality around the world. Interleukin (IL)-8, a proinflammatory chemokine with tumorigenic and proangiogenic effects, promotes lung cancer cells growth and migration and contributes to cell aggressive phenotypes. Integrin αvβ6 is a receptor of transm...

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Detalles Bibliográficos
Autores principales: Yan, Pengwei, Zhu, Huanfeng, Yin, Li, Wang, Lijun, Xie, Peng, Ye, Jinjun, Jiang, Xuesong, He, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002349/
https://www.ncbi.nlm.nih.gov/pubmed/29573639
http://dx.doi.org/10.1016/j.tranon.2018.02.013