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Chimeric HCMV/HSV-1 and Δγ(1)34.5 oncolytic herpes simplex virus elicit immune mediated antigliomal effect and antitumor memory()()

Malignant gliomas are the most common primary brain tumor and are characterized by rapid and highly invasive growth. Because of their poor prognosis, new therapeutic strategies are needed. Oncolytic virotherapy (OV) is a promising strategy for treating cancer that incorporates both direct viral repl...

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Detalles Bibliográficos
Autores principales: Ghonime, Mohammed G., Jackson, Josh, Shah, Amish, Roth, Justin, Li, Mao, Saunders, Ute, Coleman, Jennifer, Gillespie, G. Yancey, Markert, James M., Cassady, Kevin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002352/
https://www.ncbi.nlm.nih.gov/pubmed/29216507
http://dx.doi.org/10.1016/j.tranon.2017.10.005