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Deregulation of UBE2C-mediated autophagy repression aggravates NSCLC progression

The roles of aberrantly regulated autophagy in human malignancy and the mechanisms that initiate and sustain the repression of autophagy in carcinogenesis are less well defined. Activation of the oncogene UBE2C and repression of autophagy are concurrently underlying the initiation, progression, and...

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Detalles Bibliográficos
Autores principales: Guo, Jiwei, Wu, Yan, Du, Jing, Yang, Lijuan, Chen, Weiwei, Gong, Kaikai, Dai, Juanjuan, Miao, Shuang, Jin, Dan, Xi, Sichuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002383/
https://www.ncbi.nlm.nih.gov/pubmed/29904125
http://dx.doi.org/10.1038/s41389-018-0054-6