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Decreased monocyte shedding of the migration inhibitor soluble CD18 in alcoholic hepatitis

OBJECTIVES: During alcoholic hepatitis (AH) monocytes traverse the vascular boundaries and massively invade the liver. In principle, tissue extravasation can be limited through shedding of CD18 integrins from leukocytes, including monocytes. The soluble (s) product sCD18 conceals adhesion receptors...

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Detalles Bibliográficos
Autores principales: Støy, Sidsel, Sandahl, Thomas Damgaard, Hansen, Anne Louise, Deleuran, Bent, Vorup-Jensen, Thomas, Vilstrup, Hendrik, Kragstrup, Tue Wenzel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002386/
https://www.ncbi.nlm.nih.gov/pubmed/29904132
http://dx.doi.org/10.1038/s41424-018-0022-7