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Decreased monocyte shedding of the migration inhibitor soluble CD18 in alcoholic hepatitis
OBJECTIVES: During alcoholic hepatitis (AH) monocytes traverse the vascular boundaries and massively invade the liver. In principle, tissue extravasation can be limited through shedding of CD18 integrins from leukocytes, including monocytes. The soluble (s) product sCD18 conceals adhesion receptors...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002386/ https://www.ncbi.nlm.nih.gov/pubmed/29904132 http://dx.doi.org/10.1038/s41424-018-0022-7 |