Cargando…

WNK1 regulates skeletal muscle cell hypertrophy by modulating the nuclear localization and transcriptional activity of FOXO4

With-no-lysine (K) (WNK) kinases, which are mutated in the inherited form of hypertension pseudohypoaldosteronism type II, are essential regulators of membrane ion transporters. Here, we report that WNK1 positively regulates skeletal muscle cell hypertrophy via mediating the function of the pro-long...

Descripción completa

Detalles Bibliográficos
Autores principales: Mandai, Shintaro, Mori, Takayasu, Nomura, Naohiro, Furusho, Taisuke, Arai, Yohei, Kikuchi, Hiroaki, Sasaki, Emi, Sohara, Eisei, Rai, Tatemitsu, Uchida, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002401/
https://www.ncbi.nlm.nih.gov/pubmed/29904119
http://dx.doi.org/10.1038/s41598-018-27414-0