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WNK1 regulates skeletal muscle cell hypertrophy by modulating the nuclear localization and transcriptional activity of FOXO4
With-no-lysine (K) (WNK) kinases, which are mutated in the inherited form of hypertension pseudohypoaldosteronism type II, are essential regulators of membrane ion transporters. Here, we report that WNK1 positively regulates skeletal muscle cell hypertrophy via mediating the function of the pro-long...
Autores principales: | Mandai, Shintaro, Mori, Takayasu, Nomura, Naohiro, Furusho, Taisuke, Arai, Yohei, Kikuchi, Hiroaki, Sasaki, Emi, Sohara, Eisei, Rai, Tatemitsu, Uchida, Shinichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002401/ https://www.ncbi.nlm.nih.gov/pubmed/29904119 http://dx.doi.org/10.1038/s41598-018-27414-0 |
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