Pharmacological activation of epidermal growth factor receptor signaling inhibits colitis-associated cancer in mice

Current treatments for inflammatory bowel disease (IBD) target the overactive immune response of the intestinal mucosa. However, epidermal growth factor (EGF), an activating ligand of the EGF receptor (EGFR), has been shown to induce disease remission through direct targeting of intestinal mucosal h...

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Detalles Bibliográficos
Autores principales: Dubé, Philip E., Liu, Cambrian Y., Girish, Nandini, Washington, M. Kay, Polk, D. Brent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002410/
https://www.ncbi.nlm.nih.gov/pubmed/29904166
http://dx.doi.org/10.1038/s41598-018-27353-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002410/
https://www.ncbi.nlm.nih.gov/pubmed/29904166
http://dx.doi.org/10.1038/s41598-018-27353-w

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