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Pharmacological activation of epidermal growth factor receptor signaling inhibits colitis-associated cancer in mice
Current treatments for inflammatory bowel disease (IBD) target the overactive immune response of the intestinal mucosa. However, epidermal growth factor (EGF), an activating ligand of the EGF receptor (EGFR), has been shown to induce disease remission through direct targeting of intestinal mucosal h...
Autores principales: | Dubé, Philip E., Liu, Cambrian Y., Girish, Nandini, Washington, M. Kay, Polk, D. Brent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002410/ https://www.ncbi.nlm.nih.gov/pubmed/29904166 http://dx.doi.org/10.1038/s41598-018-27353-w |
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