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JIP3 localises to exocytic vesicles and focal adhesions in the growth cones of differentiated PC12 cells

The JNK-interacting protein 3 (JIP3) is a molecular scaffold, expressed predominantly in neurons, that serves to coordinate the activation of the c-Jun N-terminal kinase (JNK) by binding to JNK and the upstream kinases involved in its activation. The JNK pathway is involved in the regulation of many...

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Detalles Bibliográficos
Autores principales: Caswell, Patrick T., Dickens, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002436/
https://www.ncbi.nlm.nih.gov/pubmed/29159770
http://dx.doi.org/10.1007/s11010-017-3222-7