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Inhibitory influence of natural flavonoids on human protein kinase CK2 isoforms: effect of the regulatory subunit

CK2 is a pleiotropic, constitutively active protein kinase responsible for the phosphorylation of more than 300 physiological substrates. Typically, this enzyme is found in tetrameric form consisting of two regulatory subunits CK2β and two catalytic subunits CK2α or CK2α′. Several natural occurring...

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Detalles Bibliográficos
Autores principales: Baier, Andrea, Nazaruk, Jolanta, Galicka, Anna, Szyszka, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002439/
https://www.ncbi.nlm.nih.gov/pubmed/29188536
http://dx.doi.org/10.1007/s11010-017-3228-1