The source of cell-free mitochondrial DNA in trauma and potential therapeutic strategies

Mitochondria play a key role in the pathophysiology of post-injury inflammation. Cell-free mitochondrial DNA (cf-mtDNA) is now understood to catalyse sterile inflammation after trauma. Observations in trauma cohorts have identified high cf-mtDNA in patients with systemic inflammatory response syndro...

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Detalles Bibliográficos
Autores principales: Thurairajah, Kabilan, Briggs, Gabrielle Daisy, Balogh, Zsolt Janos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002458/
https://www.ncbi.nlm.nih.gov/pubmed/29633007
http://dx.doi.org/10.1007/s00068-018-0954-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002458/
https://www.ncbi.nlm.nih.gov/pubmed/29633007
http://dx.doi.org/10.1007/s00068-018-0954-3

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