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Building predictive in vitro pulmonary toxicity assays using high-throughput imaging and artificial intelligence

Human lungs are susceptible to the toxicity induced by soluble xenobiotics. However, the direct cellular effects of many pulmonotoxic chemicals are not always clear, and thus, a general in vitro assay for testing pulmonotoxicity applicable to a wide variety of chemicals is not currently available. H...

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Detalles Bibliográficos
Autores principales: Lee, Jia-Ying Joey, Miller, James Alastair, Basu, Sreetama, Kee, Ting-Zhen Vanessa, Loo, Lit-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002469/
https://www.ncbi.nlm.nih.gov/pubmed/29705884
http://dx.doi.org/10.1007/s00204-018-2213-0