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Human P2Y(11) Expression Level Affects Human P2X7 Receptor-Mediated Cell Death

Adenosine triphosphate (ATP) is known to induce cell death in T lymphocytes at high extracellular concentrations. CD4(+) and CD8(+) T lymphocytes have a differential response to ATP, which in mice is due to differences in the P2X7 receptor expression levels. By contrast, we observed that the differe...

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Detalles Bibliográficos
Autores principales: Dreisig, Karin, Sund, Louise, Dommer, Maja Wallentin, Kristensen, Nikolaj Pagh, Boddum, Kim, Viste, Rannveig, Fredholm, Simon, Odum, Niels, Jäättelä, Marja, Skov, Søren, Kornum, Birgitte R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002484/
https://www.ncbi.nlm.nih.gov/pubmed/29937766
http://dx.doi.org/10.3389/fimmu.2018.01159