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Type 2 Diabetes Leads to Axon Initial Segment Shortening in db/db Mice

Cognitive and mood impairments are common central nervous system complications of type 2 diabetes, although the neuronal mechanism(s) remains elusive. Previous studies focused mainly on neuronal inputs such as altered synaptic plasticity. Axon initial segment (AIS) is a specialized functional domain...

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Detalles Bibliográficos
Autores principales: Yermakov, Leonid M., Drouet, Domenica E., Griggs, Ryan B., Elased, Khalid M., Susuki, Keiichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002488/
https://www.ncbi.nlm.nih.gov/pubmed/29937715
http://dx.doi.org/10.3389/fncel.2018.00146