HMGA1a Induces Alternative Splicing of the Estrogen Receptor-αlpha Gene by Trapping U1 snRNP to an Upstream Pseudo-5′ Splice Site

Objectives: The high-mobility group A protein 1a (HMGA1a) protein is known as a transcription factor that binds to DNA, but recent studies have shown it exerts novel functions through RNA-binding. We were prompted to decipher the mechanism of HMGA1a-induced alternative splicing of the estrogen recep...

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Detalles Bibliográficos
Autores principales: Ohe, Kenji, Miyajima, Shinsuke, Tanaka, Tomoko, Hamaguchi, Yuriko, Harada, Yoshihiro, Horita, Yuta, Beppu, Yuki, Ito, Fumiaki, Yamasaki, Takafumi, Terai, Hiroki, Mori, Masayoshi, Murata, Yusuke, Tanabe, Makito, Abe, Ichiro, Ashida, Kenji, Kobayashi, Kunihisa, Enjoji, Munechika, Nomiyama, Takashi, Yanase, Toshihiko, Harada, Nobuhiro, Utsumi, Toshiaki, Mayeda, Akila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002489/
https://www.ncbi.nlm.nih.gov/pubmed/29938207
http://dx.doi.org/10.3389/fmolb.2018.00052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002489/
https://www.ncbi.nlm.nih.gov/pubmed/29938207
http://dx.doi.org/10.3389/fmolb.2018.00052

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