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Conic shapes have higher sensitivity than cylindrical ones in nanopore DNA sequencing

Nanopores have emerged as helpful research tools for single molecule detection. Through continuum modeling, we investigated the effects of membrane thickness, nanopore size, and pore shape on current signal characteristics of DNA. The simulation results showed that, when reducing the pore diameter,...

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Detalles Bibliográficos
Autores principales: Tu, Bin, Bai, Shiyang, Lu, Benzhuo, Fang, Qiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002541/
https://www.ncbi.nlm.nih.gov/pubmed/29904117
http://dx.doi.org/10.1038/s41598-018-27517-8