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Conic shapes have higher sensitivity than cylindrical ones in nanopore DNA sequencing
Nanopores have emerged as helpful research tools for single molecule detection. Through continuum modeling, we investigated the effects of membrane thickness, nanopore size, and pore shape on current signal characteristics of DNA. The simulation results showed that, when reducing the pore diameter,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002541/ https://www.ncbi.nlm.nih.gov/pubmed/29904117 http://dx.doi.org/10.1038/s41598-018-27517-8 |