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Polymorphism of the 86th amino acid in CX26 protein and hereditary deafness

OBJECTIVE: To investigate the membrane localization function of the CX26 protein when its 86th amino acid is Thr, Ser or Arg, and its relations to deafness. METHODS: CX26-GFP protein with either Thr, Ser or Arg as the 86th amino acid was expressed in mouse SGN cells via the GFP fusion type lenti-vir...

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Detalles Bibliográficos
Autores principales: Shi, Xi, Qiu, Shiwei, Yan, Fendong, Shi, Lizhang, Xuan, Yili, Zhuang, Wei, Bei, Yingli, Yao, Hanli, Yuan, Na, Yang, Shiming, Qiao, Yuehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese PLA General Hospital 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002600/
https://www.ncbi.nlm.nih.gov/pubmed/29937815
http://dx.doi.org/10.1016/j.joto.2016.05.004