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Mass Spectrometry-Based Method to Study Inhibitor-Induced Metabolic Redirection in the Central Metabolism of Cancer Cells

Cancer cells often respond to chemotherapeutic inhibitors by redirecting carbon flow in the central metabolism. To understand the metabolic redirections of inhibitor treatment on cancer cells, this study established a (13)C-metabolic flux analysis ((13)C-MFA)-based method to evaluate metabolic redir...

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Detalles Bibliográficos
Autores principales: Araki, Chie, Okahashi, Nobuyuki, Maeda, Kousuke, Shimizu, Hiroshi, Matsuda, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Mass Spectrometry Society of Japan 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002601/
https://www.ncbi.nlm.nih.gov/pubmed/29922569
http://dx.doi.org/10.5702/massspectrometry.A0067