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Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection

Characterization of single antibody lineages within infected individuals has provided insights into the development of Env-specific antibodies. However, a systems-level understanding of the humoral response against HIV-1 is limited. Here, we interrogated the antibody repertoires of multiple HIV-infe...

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Detalles Bibliográficos
Autores principales: Setliff, Ian, McDonnell, Wyatt J., Raju, Nagarajan, Bombardi, Robin G., Murji, Amyn A., Scheepers, Cathrine, Ziki, Rutendo, Mynhardt, Charissa, Shepherd, Bryan E., Mamchak, Alusha A., Garrett, Nigel, Karim, Salim Abdool, Mallal, Simon A., Crowe, James E., Morris, Lynn, Georgiev, Ivelin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002606/
https://www.ncbi.nlm.nih.gov/pubmed/29861170
http://dx.doi.org/10.1016/j.chom.2018.05.001