The Bicarbonate Transporter SLC4A7 Plays a Key Role in Macrophage Phagosome Acidification

Macrophages represent the first line of immune defense against pathogens, and phagosome acidification is a necessary step in pathogen clearance. Here, we identified the bicarbonate transporter SLC4A7, which is strongly induced upon macrophage differentiation, as critical for phagosome acidification....

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Detalles Bibliográficos
Autores principales: Sedlyarov, Vitaly, Eichner, Ruth, Girardi, Enrico, Essletzbichler, Patrick, Goldmann, Ulrich, Nunes-Hasler, Paula, Srndic, Ismet, Moskovskich, Anna, Heinz, Leonhard X., Kartnig, Felix, Bigenzahn, Johannes W., Rebsamen, Manuele, Kovarik, Pavel, Demaurex, Nicolas, Superti-Furga, Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002608/
https://www.ncbi.nlm.nih.gov/pubmed/29779931
http://dx.doi.org/10.1016/j.chom.2018.04.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002608/
https://www.ncbi.nlm.nih.gov/pubmed/29779931
http://dx.doi.org/10.1016/j.chom.2018.04.013

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