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Neutralizing Antibody Responses following Long-Term Vaccination with HIV-1 Env gp140 in Guinea Pigs

A vaccination regimen capable of eliciting potent and broadly neutralizing antibodies (bNAbs) remains an unachieved goal of the HIV-1 vaccine field. Here, we report the immunogenicity of longitudinal prime/boost vaccination regimens with a panel of HIV-1 envelope (Env) gp140 protein immunogens over...

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Detalles Bibliográficos
Autores principales: Bricault, Christine A., Kovacs, James M., Badamchi-Zadeh, Alexander, McKee, Krisha, Shields, Jennifer L., Gunn, Bronwyn M., Neubauer, George H., Ghantous, Fadi, Jennings, Julia, Gillis, Lindsey, Perry, James, Nkolola, Joseph P., Alter, Galit, Chen, Bing, Stephenson, Kathryn E., Doria-Rose, Nicole, Mascola, John R., Seaman, Michael S., Barouch, Dan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002713/
https://www.ncbi.nlm.nih.gov/pubmed/29643249
http://dx.doi.org/10.1128/JVI.00369-18