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Genome-wide surveys reveal polarity and cytoskeletal regulators mediate LKB1-associated germline stem cell quiescence

BACKGROUND: Caenorhabditis elegans can endure long periods of environmental stress by altering their development to execute a quiescent state called “dauer”. Previous work has implicated LKB1 - the causative gene in the autosomal dominant, cancer pre-disposing disease called Peutz-Jeghers Syndrome (...

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Detalles Bibliográficos
Autores principales: Kadekar, Pratik, Chaouni, Rita, Clark, Emily, Kazanets, Anna, Roy, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003023/
https://www.ncbi.nlm.nih.gov/pubmed/29907081
http://dx.doi.org/10.1186/s12864-018-4847-y