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Activation and polarization of circulating monocytes in severe chronic obstructive pulmonary disease

BACKGROUND: The ability of circulating monocytes to develop into lung macrophages and promote lung tissue damage depends upon their phenotypic pattern of differentiation and activation. Whether this phenotypic pattern varies with COPD severity is unknown. Here we characterize the activation and diff...

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Detalles Bibliográficos
Autores principales: Cornwell, William D., Kim, Victor, Fan, Xiaoxuan, Vega, Marie Elena, Ramsey, Frederick V., Criner, Gerard J., Rogers, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003040/
https://www.ncbi.nlm.nih.gov/pubmed/29907106
http://dx.doi.org/10.1186/s12890-018-0664-y