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Emerging roles and regulation of MiT/TFE transcriptional factors

The MiT/TFE transcription factors play a pivotal role in the regulation of autophagy and lysosomal biogenesis. The subcellular localization and activity of MiT/TFE proteins are primarily regulated through phosphorylation. And the phosphorylated protein is retained in the cytoplasm and subsequently t...

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Detalles Bibliográficos
Autores principales: Yang, Min, Liu, En, Tang, Li, Lei, Yuanyuan, Sun, Xuemei, Hu, Jiaxi, Dong, Hui, Yang, Shi-Ming, Gao, Mingfa, Tang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003119/
https://www.ncbi.nlm.nih.gov/pubmed/29903018
http://dx.doi.org/10.1186/s12964-018-0242-1