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A rare CHD5 haplotype and its interactions with environmental factors predicting hepatocellular carcinoma risk

BACKGROUND: CHD5 is a conventional tumour-suppressing gene in many tumours. The aim of this study was to determine whether CHD5 variants contribute to the risk of hepatocellular carcinoma (HCC). METHODS: Gene variants were identified using next-generation sequencing targeted on referenced mutations...

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Detalles Bibliográficos
Autores principales: Xiao, Qin, Chen, Lianzhou, Luo, Haiqing, Li, Hongmei, Kong, Qingming, Jiao, Fei, Pang, Shifeng, Zhang, Ming, Lan, Feifei, Fan, Wenguo, Luo, Hui, Tao, Tao, Zhu, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003142/
https://www.ncbi.nlm.nih.gov/pubmed/29907144
http://dx.doi.org/10.1186/s12885-018-4551-y