Cargando…

Development and application of an integrated allele-specific pipeline for methylomic and epigenomic analysis (MEA)

BACKGROUND: Allele-specific transcriptional regulation, including of imprinted genes, is essential for normal mammalian development. While the regulatory regions controlling imprinted genes are associated with DNA methylation (DNAme) and specific histone modifications, the interplay between transcri...

Descripción completa

Detalles Bibliográficos
Autores principales: Richard Albert, Julien, Koike, Tasuku, Younesy, Hamid, Thompson, Richard, Bogutz, Aaron B., Karimi, Mohammad M., Lorincz, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003194/
https://www.ncbi.nlm.nih.gov/pubmed/29907088
http://dx.doi.org/10.1186/s12864-018-4835-2