Two Ck1δ transcripts regulated by m6A methylation code for two antagonistic kinases in the control of the circadian clock

The N(6)-methylation of internal adenosines (m6A) in mRNA has been quantified and localized throughout the transcriptome. However, the physiological significance of m6A in most highly methylated mRNAs is unknown. It was demonstrated previously that the circadian clock, based on transcription-transla...

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Detalles Bibliográficos
Autores principales: Fustin, Jean-Michel, Kojima, Rika, Itoh, Kakeru, Chang, Hsin-Yi, Ye, Shiqi, Zhuang, Bowen, Oji, Asami, Gibo, Shingo, Narasimamurthy, Rajesh, Virshup, David, Kurosawa, Gen, Doi, Masao, Manabe, Ichiro, Ishihama, Yasushi, Ikawa, Masahito, Okamura, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003373/
https://www.ncbi.nlm.nih.gov/pubmed/29784786
http://dx.doi.org/10.1073/pnas.1721371115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003373/
https://www.ncbi.nlm.nih.gov/pubmed/29784786
http://dx.doi.org/10.1073/pnas.1721371115

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