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Two Ck1δ transcripts regulated by m6A methylation code for two antagonistic kinases in the control of the circadian clock
The N(6)-methylation of internal adenosines (m6A) in mRNA has been quantified and localized throughout the transcriptome. However, the physiological significance of m6A in most highly methylated mRNAs is unknown. It was demonstrated previously that the circadian clock, based on transcription-transla...
Autores principales: | Fustin, Jean-Michel, Kojima, Rika, Itoh, Kakeru, Chang, Hsin-Yi, Ye, Shiqi, Zhuang, Bowen, Oji, Asami, Gibo, Shingo, Narasimamurthy, Rajesh, Virshup, David, Kurosawa, Gen, Doi, Masao, Manabe, Ichiro, Ishihama, Yasushi, Ikawa, Masahito, Okamura, Hitoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003373/ https://www.ncbi.nlm.nih.gov/pubmed/29784786 http://dx.doi.org/10.1073/pnas.1721371115 |
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