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Laterally confined growth of cells induces nuclear reprogramming in the absence of exogenous biochemical factors
Cells in tissues undergo transdifferentiation programs when stimulated by specific mechanical and biochemical signals. While seminal studies have demonstrated that exogenous biochemical factors can reprogram somatic cells into pluripotent stem cells, the critical roles played by mechanical signals i...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003522/ https://www.ncbi.nlm.nih.gov/pubmed/29735717 http://dx.doi.org/10.1073/pnas.1714770115 |