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CD73 expression and clinical significance in human metastatic melanoma

BACKGROUND: CD73 is an ectoenzyme involved in the production of adenosine. It exerts immunosuppressive and protumoral roles and has emerged as a potential immuno-oncology target. RESULTS: CD73 expression was detected in TC in 54% of melanoma metastases, involving < 50% TC in the majority of the c...

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Detalles Bibliográficos
Autores principales: Monteiro, Inês, Vigano, Selena, Faouzi, Mohamed, Treilleux, Isabelle, Michielin, Olivier, Ménétrier-Caux, Christine, Caux, Christophe, Romero, Pedro, de Leval, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003551/
https://www.ncbi.nlm.nih.gov/pubmed/29928476
http://dx.doi.org/10.18632/oncotarget.25426