Integrated epigenetic and genetic analysis identifies markers of prognostic significance in pediatric acute myeloid leukemia

Acute myeloid leukemia (AML) may be an epigenetically-driven malignancy because it harbors fewer genomic mutations than other cancers. In recent studies of AML in adults, DNA methylation patterns associate with clinical risk groups and prognosis. However, thorough evaluations of methylation in pedia...

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Detalles Bibliográficos
Autores principales: Lamba, Jatinder K., Cao, Xueyuan, Raimondi, Susana C., Rafiee, Roya, Downing, James R., Lei, Shi, Gruber, Tanja, Ribeiro, Raul C., Rubnitz, Jeffrey E., Pounds, Stanley B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003565/
https://www.ncbi.nlm.nih.gov/pubmed/29928480
http://dx.doi.org/10.18632/oncotarget.25475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003565/
https://www.ncbi.nlm.nih.gov/pubmed/29928480
http://dx.doi.org/10.18632/oncotarget.25475

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