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Integrated epigenetic and genetic analysis identifies markers of prognostic significance in pediatric acute myeloid leukemia
Acute myeloid leukemia (AML) may be an epigenetically-driven malignancy because it harbors fewer genomic mutations than other cancers. In recent studies of AML in adults, DNA methylation patterns associate with clinical risk groups and prognosis. However, thorough evaluations of methylation in pedia...
Autores principales: | Lamba, Jatinder K., Cao, Xueyuan, Raimondi, Susana C., Rafiee, Roya, Downing, James R., Lei, Shi, Gruber, Tanja, Ribeiro, Raul C., Rubnitz, Jeffrey E., Pounds, Stanley B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003565/ https://www.ncbi.nlm.nih.gov/pubmed/29928480 http://dx.doi.org/10.18632/oncotarget.25475 |
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