Cargando…

Cryptotanshinone hinders renal fibrosis and epithelial transdifferentiation in obstructive nephropathy by inhibiting TGF-β1/Smad3/integrin β1 signal

Recent studies have reported that CTS can alleviate cardiac fibrosis. However, the effects of CTS on kidney fibrosis and EMT are still unknown. This study explored whether CTS could attenuate tubulointerstitial fibrosis as well as EMT, and investigated the potential underlying mechanisms. In this st...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Wei, Zhou, Pang-Hu, Hu, Wei, Xu, Chang-Geng, Zhou, Xiang-Jun, Liang, Chao-Zhao, Zhang, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003568/ https://www.ncbi.nlm.nih.gov/pubmed/29928474 http://dx.doi.org/10.18632/oncotarget.23803

Ejemplares similares

SKLB023 hinders renal interstitial fibrosis in obstructive nephropathy by interfering TGF-β1/Smad3 signaling
por: Feng, Yanhuan, et al.
Publicado: (2018)

Ganoderic acid hinders renal fibrosis via suppressing the TGF-β/Smad and MAPK signaling pathways
por: Geng, Xiao-qiang, et al.
Publicado: (2019)

Sitagliptin ameliorates diabetic nephropathy by blocking TGF-β1/Smad signaling pathway
por: Wang, Dongdong, et al.
Publicado: (2018)

Lefty-1 alleviates TGF-β1-induced fibroblast–myofibroblast transdifferentiation in NRK-49F cells
por: Zhang, Lijun, et al.
Publicado: (2015)

Aspirin attenuates liver fibrosis by suppressing TGF-β1/Smad signaling
por: Sun, Yimin, et al.
Publicado: (2022)

TGF-β/Smad signaling in renal fibrosis
por: Meng, Xiao-Ming, et al.
Publicado: (2015)

P311 promotes renal fibrosis via TGFβ1/Smad signaling
por: Yao, Zhihui, et al.
Publicado: (2015)

Localization of αυβ6 Integrin-TGF-β1/Smad3, mTOR and PPARγ in Experimental Colorectal Fibrosis
por: Latella, G., et al.
Publicado: (2013)

TGF-β/Smad Signaling Pathway in Tubulointerstitial Fibrosis
por: Yu, Xiao-Yong, et al.
Publicado: (2022)

TGF-β1 Induced Transdifferentiation of RPE Cells is Mediated by TAK1
por: Dvashi, Zeev, et al.
Publicado: (2015)

Wogonin Ameliorates Renal Inflammation and Fibrosis by Inhibiting NF-κB and TGF-β1/Smad3 Signaling Pathways in Diabetic Nephropathy
por: Zheng, Zhi-chao, et al.
Publicado: (2020)

TGF-β1/Smads and miR-21 in Renal Fibrosis and Inflammation
por: Loboda, Agnieszka, et al.
Publicado: (2016)

Plasma Gelsolin Induced Glomerular Fibrosis via the TGF-β1/Smads Signal Transduction Pathway in IgA Nephropathy
por: Zhang, Lei, et al.
Publicado: (2017)

Shenqiwan Ameliorates Renal Fibrosis in Rats by Inhibiting TGF-β1/Smads Signaling Pathway
por: Chen, Hongshu, et al.
Publicado: (2017)

Aspirin inhibits endometrial fibrosis by suppressing the TGF-β1-Smad2/Smad3 pathway in intrauterine adhesions
por: Zhang, Zihui, et al.
Publicado: (2020)

Diverse Roles of TGF-β/Smads in Renal Fibrosis and Inflammation
por: Lan, Hui Yao
Publicado: (2011)

Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis
por: Walton, Kelly L., et al.
Publicado: (2017)

Effect of echinacoside on kidney fibrosis by inhibition of TGF-β1/Smads signaling pathway in the db/db mice model of diabetic nephropathy
por: Tang, Fengjuan, et al.
Publicado: (2017)

Astragaloside Inhibits Hepatic Fibrosis by Modulation of TGF-β1/Smad Signaling Pathway
por: Yuan, Xingxing, et al.
Publicado: (2018)

MiR-10a improves hepatic fibrosis by regulating the TGFβl/Smads signal transduction pathway
por: Zhou, Guangyao, et al.
Publicado: (2016)

Chitosan oligosaccharide alleviates renal fibrosis through reducing oxidative stress damage and regulating TGF-β1/Smads pathway
por: Wu, Jun, et al.
Publicado: (2022)

FoxO1 regulates adipose transdifferentiation and iron influx by mediating Tgfβ1 signaling pathway
por: Shi, Limin, et al.
Publicado: (2023)

Emodin Retarded Renal Fibrosis Through Regulating HGF and TGFβ–Smad Signaling Pathway
por: Yang, Fan, et al.
Publicado: (2020)

β-Sitosterol Inhibits The Proliferation of Endometrial Cells via Regulating Smad7-Mediated TGF-β/Smads Signaling Pathway
por: Wen, Yi, et al.
Publicado: (2023)

Tangshen Formula Improves Diabetes-Associated Myocardial Fibrosis by Inhibiting TGF-β/Smads and Wnt/β-Catenin Pathways
por: Hu, Lin, et al.
Publicado: (2021)

Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways
por: Liu, Ning, et al.
Publicado: (2019)

MicroRNA-130a attenuates cardiac fibrosis after myocardial infarction through TGF-β/Smad signaling by directly targeting TGF-β receptor 1
por: Feng, Yu, et al.
Publicado: (2022)

Catalpol Protects Against Pulmonary Fibrosis Through Inhibiting TGF-β1/Smad3 and Wnt/β-Catenin Signaling Pathways
por: Yang, Fan, et al.
Publicado: (2021)

Astragaloside IV alleviates silica-induced pulmonary fibrosis via inactivation of the TGF-β1/Smad2/3 signaling pathway
por: Li, Nannan, et al.
Publicado: (2021)

Cilomilast Ameliorates Renal Tubulointerstitial Fibrosis by Inhibiting the TGF-β1-Smad2/3 Signaling Pathway
por: Xu, Man, et al.
Publicado: (2021)

Liuwei Dihuang Pill Attenuates Diabetic Nephropathy by Inhibiting Renal Fibrosis via TGF-β/Smad2/3 Pathway
por: Shu, Shi, et al.
Publicado: (2022)

Kangfuxin Oral Liquid Attenuates Bleomycin-Induced Pulmonary Fibrosis via the TGF-β1/Smad Pathway
por: Yao, Huan, et al.
Publicado: (2019)

Tanshinone IIA regulates the TGF-β1/Smad signaling pathway to ameliorate non-alcoholic steatohepatitis-related fibrosis
por: Xu, Lianjie, et al.
Publicado: (2022)

TGF-β is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasion
por: Joseph, J V, et al.
Publicado: (2014)

MEK inhibition prevents TGF-β1-induced myofibroblast transdifferentiation in human tenon fibroblasts
por: Wen, Jiamin, et al.
Publicado: (2019)

PU.1 inhibition attenuates atrial fibrosis and atrial fibrillation vulnerability induced by angiotensin‐II by reducing TGF‐β1/Smads pathway activation
por: Hu, Juan, et al.
Publicado: (2021)

Bellidifolin Ameliorates Isoprenaline-Induced Myocardial Fibrosis by Regulating TGF-β1/Smads and p38 Signaling and Preventing NR4A1 Cytoplasmic Localization
por: Yang, Hong-Xia, et al.
Publicado: (2021)

AR12286 Alleviates TGF-β-Related Myofibroblast Transdifferentiation and Reduces Fibrosis after Glaucoma Filtration Surgery
por: Cheng, Wen-Sheng, et al.
Publicado: (2020)

Rejuvenation by inhibiting TGF-β1/pSmad signaling
por: Corder, Elizabeth H., et al.
Publicado: (2015)

β3 Integrin Promotes TGF-β1/H(2)O(2)/HOCl-Mediated Induction of Metastatic Phenotype of Hepatocellular Carcinoma Cells by Enhancing TGF-β1 Signaling
por: Feng, Xin-Xia, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_a349ceia9ofeng9e4c1bd1n6df