miR-146a suppresses 5-lipoxygenase activating protein (FLAP) expression and Leukotriene B4 production in lung cancer cells

Arachidonic acid (AA) can be converted into prostaglandins (PGs) or leukotrienes (LTs) by the enzymatic actions of cyclooxygenases (COX-1 and COX-2) or 5-lipoxygenase (5-LO), respectively. PGs and LTs are lipid signaling molecules that have been implicated in various diseases, including multiple can...

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Detalles Bibliográficos
Autores principales: Iacona, Joseph R., Monteleone, Nicholas J., Lutz, Carol S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003571/
https://www.ncbi.nlm.nih.gov/pubmed/29928483
http://dx.doi.org/10.18632/oncotarget.25482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003571/
https://www.ncbi.nlm.nih.gov/pubmed/29928483
http://dx.doi.org/10.18632/oncotarget.25482

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